The course aims to teach the general aspects of the structure and function of the mammalian cell and tissues. The goal of this course is to enable students to recognize the cell and tissue structure under the optical microscope.
teacher profile teaching materials
Applied skills: The basic knowledge acquired through the study of cytology will allow students to apply them to the study of tissues. In addition, students will be able to recognize and comment on a preparation or photograph acquired with a microscopic instrument. Finally, this knowledge will allow students to understand the disciplinary insights that will be carried out in the following years.
Cytology.
Cell theory. Methods of studying the cell: the microscope.
Macromolecules: The main carbohydrates of biological interest and their polymers. Notes on glycolysis. The main lipids of biological interest. Amino acids and proteins. Notes on the structure and function of proteins. Enzymes.
Nucleic acids. DNA and RNA structure. DNA replication, messenger transcription and RNA, genetic code, ribosomes and protein synthesis.
Cell membranes: chemical composition, The fluid mosaic model. Intrinsic and extrinsic proteins. Permeability and active transport. Ionic channels. Intercellular junctions: zonula occludens, zonula adherens and desmosomes.
Cytoplasmic and secretory pathway, The endoplasmic reticulum, Origin and sorting of secretory and membrane proteins. Golgi apparatus. Lysosomes, peroxisomes, endocytosis, phagocytosis, exocytosis.
Structure of mitochondria, Probable origin of mitochondria and plastids, DNA in mitochondria, Notes on energy metabolism: respiration.
The cytoskeleton: Microtubules, microfilaments and intermediate filaments.
The nucleus of eukaryotes, nuclear envelope and nuclear pores, histones and nucleosomes. Euchromatin and heterochromatin. The nucleolus. Chromosome structure.
The cell cycle: the interphase (phases G1, S and G2), Cell division. Haploid, diploid and polyploid cells. Mitosis in animal cells. Meiosis. Phases and sub-phases of meiosis. The meaning of meiosis and crossing over. Recombination.
Histology
Epithelial tissue. General characteristics. Coating epithelia. Classification and functions. The basal lamina.
Connective tissue. The different connective tissues: general characteristics and specific characteristics of the different connective tissues. The connective proper. Classification of connectives. Extracellular matrix. Connective cells and their function.
Blood and signs of cellular immunology. The plasma: composition and functions. Erythrocytes and white blood cells: morphological and functional characteristics.
Bone tissue. Spongy bone and compact bone. Microscopic structure of the bone: the osteone. Osteoblasts, osteocytes, osteoclasts.
Muscle tissue. Smooth muscle tissue. Skeletal muscle tissue. Structure and ultrastructure of muscle fiber. Myofibrils and myofilaments: the sarcomere. Muscle contraction. Heart muscle tissue.
Nervous tissue. The central and peripheral nervous system. Morphology of the neuron. Notes on nerve impulse conduction. The synapse. Neurotransmitters. Neuroglia.
Essential Cell Biology, Bruce Alberts, Karen Hopkin, Alexander D. Johnson, David Morgan, Martin Raff. Garland Science. Last edition
Histology
Junqueira's Basic Histology: Text and Atlas, Anthony Mescher. Lange. Last edition
Mutuazione: 20410235 CITOLOGIA E ISTOLOGIA in Scienze biologiche L-13 COLASANTI MARCO, Proietti Riccardo
Programme
Knowledge and understanding: Knowledge of the principles of cell biology and tissue organization. Acquisition of conscious judgment autonomy with reference to: evaluation, interpretation and contextualization of photographs acquired with microscopic techniques. Ability to communicate effectively and with the correct terminology;Applied skills: The basic knowledge acquired through the study of cytology will allow students to apply them to the study of tissues. In addition, students will be able to recognize and comment on a preparation or photograph acquired with a microscopic instrument. Finally, this knowledge will allow students to understand the disciplinary insights that will be carried out in the following years.
Cytology.
Cell theory. Methods of studying the cell: the microscope.
Macromolecules: The main carbohydrates of biological interest and their polymers. Notes on glycolysis. The main lipids of biological interest. Amino acids and proteins. Notes on the structure and function of proteins. Enzymes.
Nucleic acids. DNA and RNA structure. DNA replication, messenger transcription and RNA, genetic code, ribosomes and protein synthesis.
Cell membranes: chemical composition, The fluid mosaic model. Intrinsic and extrinsic proteins. Permeability and active transport. Ionic channels. Intercellular junctions: zonula occludens, zonula adherens and desmosomes.
Cytoplasmic and secretory pathway, The endoplasmic reticulum, Origin and sorting of secretory and membrane proteins. Golgi apparatus. Lysosomes, peroxisomes, endocytosis, phagocytosis, exocytosis.
Structure of mitochondria, Probable origin of mitochondria and plastids, DNA in mitochondria, Notes on energy metabolism: respiration.
The cytoskeleton: Microtubules, microfilaments and intermediate filaments.
The nucleus of eukaryotes, nuclear envelope and nuclear pores, histones and nucleosomes. Euchromatin and heterochromatin. The nucleolus. Chromosome structure.
The cell cycle: the interphase (phases G1, S and G2), Cell division. Haploid, diploid and polyploid cells. Mitosis in animal cells. Meiosis. Phases and sub-phases of meiosis. The meaning of meiosis and crossing over. Recombination.
Histology
Epithelial tissue. General characteristics. Coating epithelia. Classification and functions. The basal lamina.
Connective tissue. The different connective tissues: general characteristics and specific characteristics of the different connective tissues. The connective proper. Classification of connectives. Extracellular matrix. Connective cells and their function.
Blood and signs of cellular immunology. The plasma: composition and functions. Erythrocytes and white blood cells: morphological and functional characteristics.
Bone tissue. Spongy bone and compact bone. Microscopic structure of the bone: the osteone. Osteoblasts, osteocytes, osteoclasts.
Muscle tissue. Smooth muscle tissue. Skeletal muscle tissue. Structure and ultrastructure of muscle fiber. Myofibrils and myofilaments: the sarcomere. Muscle contraction. Heart muscle tissue.
Nervous tissue. The central and peripheral nervous system. Morphology of the neuron. Notes on nerve impulse conduction. The synapse. Neurotransmitters. Neuroglia.
Core Documentation
CytologyEssential Cell Biology, Bruce Alberts, Karen Hopkin, Alexander D. Johnson, David Morgan, Martin Raff. Garland Science. Last edition
Histology
Junqueira's Basic Histology: Text and Atlas, Anthony Mescher. Lange. Last edition
Type of delivery of the course
The course takes place with lessons and is divided into a Cytology module and a Histology module, but the topics will often be transversal. Classes are held weekly in the classroom with the help of power point presentations and videos.Attendance
Class attendance is not mandatory.Type of evaluation
The exam is ORAL. Students must register on the student's portal and are invited to present themselves on the day of the exam at the indicated time. On that date, the list of students, processed according to a random order, will be read. Each student (if present) will indicate one of the days (as proposed by the teacher) to take the exam. The assessment of profit is aimed at verifying the level of knowledge of the topics covered in the course and the reasoning ability of the student who points out that he / she knows how to connect the structure and function of the different structures. In the evaluation of the tests and in the attribution of the final grade, the following will be taken into account: the level of knowledge of the contents demonstrated, the ability to apply the theoretical concepts, the capacity for analysis, synthesis and intra- and inter-disciplinary connections, of the capacity of critical sense and formulation of judgments, of mastery of expression. The evaluation is expressed in thirtieths. Verbalization mode The exam verbalization will be carried out as follows: 1) the student does not appear at the call: absent 2) the student passes the exam but refuses the vote: withdrawn 3) the student fails the exam: rejected 4) the student passes the exam: grade from 18 to 30 (possibly honors) teacher profile teaching materials
Mutuazione: 20410235 CITOLOGIA E ISTOLOGIA in Scienze biologiche L-13 COLASANTI MARCO, Proietti Riccardo