20402360 - CELLULAR BIOCHEMISTRY

The aim of the course is to introduce students to the “inorganic biofactors”, starting from their biochemical role to the analysis of their impact on human health.
Moreover, the course will provide student the essential knowledge for understanding of the biochemical and molecular mechanism underlying metabolic, mitochondrial and neoplastic diseases.

DI MASI ALESSANDRA

teacher profile | materiale didattico

Mutuazione: 20402360 BIOCHIMICA CELLULARE in Biologia per la ricerca molecolare, cellulare e fisiopatologica LM-6 DI MASI ALESSANDRA, ASCENZI PAOLO

Programma

HEME-PROTEINS. HEME METABOLISM AND RELATED DISEASES. HEME BIOSYNTHESIS AND RELATED DISEASES. IRON METABOLISM AND RELATED DISEASES. INORGANIC BIOFACTORS: OXYGEN, CARBON MONOXIDE, NITROGEN MONOXIDE, HYDROGEN SULFIDE. BIOCHEMICAL AND CELLULAR ROLES OF THE INORGANIC BIOFACTORS. ROLE IOF THE INORGANIC BIOFACTORS IN HUMANN DISEASES ONSET. THE THERAPEUTIC USE OF THE INORGANIC BIOFACTORS. REACTIVE OXYGEN AND NITROGEN SPECIES. MITOCHONDRIAL DISEASES. THE ENERGETIC MATTER OF CANCER CELLS. THE METABOLIC REQUIREMENTS OF CANCER CELLS: THE WARBURG EFFECT.


Testi Adottati

SCIENTIFIC PAPERS SUPPLIED BY THE TEACHER.
Support texts:
Siliprandi & Tettamanti "Biochimica Medica - strutturale, metabolica e funzionale" Ed. Piccin
- Chiurchiù & Maccarrone "I radicali liberi e la loro rilevanza in biomedicina: dai meccanismi molecolari alle prospettive terapeutiche" Ed Piccin

RECEPTION TIME: Monday 10 am

Modalità Erogazione

The course of Cellular Biochemistry is a theoretical course that takes place in the second semester (March-May) of the first year and is divided into 4 hours of lectures per week with the use of PowerPoint presentations.

Modalità Valutazione

The exam consists of three written exemptions that will take place during the course semester. Each exemption will consist of three open questions. The final grade will derive from the average of the marks obtained in the three exemptions. In the event that the student has not carried out one or two exemptions or wishes to increase the grade obtained, she/he can take the oral exam in relation to the parts of the program covered by the exemption, on the established appeal dates. The student who does not intend to carry out the exemptions during the semester can directly carry out the oral exam on the established appeal dates. The final grade will evaluate the following parameters: a) Appropriateness, correctness, and congruity of acquired knowledge and skills; b) appropriate use of the specific language of the discipline; c) Expressive capacity; d) Logical skills; e) Synthesis skills; f) Ability to link different topics. Consequently, the judgment could be: a) Sufficient (from 18 to 20/30) b) Fair (from 21 to 23) c) Voucher (from 24 to 26) d) Excellent (from 27 to 29) e) Excellent (30) Praise is attributed to candidates clearly above the average, and whose possible notional, expressive, conceptual and logical limits are altogether irrelevant.

ASCENZI PAOLO

teacher profile | materiale didattico

Mutuazione: 20402360 BIOCHIMICA CELLULARE in Biologia per la ricerca molecolare, cellulare e fisiopatologica LM-6 DI MASI ALESSANDRA, ASCENZI PAOLO