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Prof.ssa ELISABETTA AFFABRIS

Contributo in Rivista

• SARS-CoV-2 Evasion of the Interferon System: Can We Restore Its Effectiveness?, SACCHI, ALESSANDRA; GIANNESSI, FLAVIA; SABATINI, ANDREA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2023Link identifier #identifier_person_191374-1 Dettaglio
• Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles, INCERPI, SANDRA; GIONFRA, FABIO; CANDELOTTI, ELENA; PERCARIO, ZULEMA ANTONIA; LEONE, STEFANO; ROSSI, MIRIAM; CARUSO, FRANCESCO SAVERIO; AFFABRIS, ELISABETTA, , 2022Link identifier #identifier_person_108283-2 Dettaglio
• HIV‐1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line, AIELLO, ALESSANDRA; GIANNESSI, FLAVIA; PERCARIO, ZULEMA ANTONIA; ARENACCIO, CLAUDIA; LEONE, STEFANO; AFFABRIS, ELISABETTA, , 2022Link identifier #identifier_person_19439-3 Dettaglio
• Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3, CANDELOTTI, ELENA; MAIOLO, MARIANGELA; GIONFRA, FABIO; PERCARIO, ZULEMA ANTONIA; POLTICELLI, FABIO; PERSICHINI, TIZIANA; COLASANTI, MARCO; AFFABRIS, ELISABETTA; INCERPI, SANDRA, , 2021Link identifier #identifier_person_91475-4 Dettaglio
• Thyroid Hormones Interaction With Immune Response, Inflammation and Non-thyroidal Illness Syndrome, GIONFRA, FABIO; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA; INCERPI, SANDRA, , 2021Link identifier #identifier_person_56199-5 Dettaglio
• Virus-induced tumorigenesis and IFN system, MANGINO, GIORGIO; AFFABRIS, ELISABETTA, , 2021Link identifier #identifier_person_149449-6 Dettaglio
• An emerging interplay between extracellular vesicles and cytokines, AIELLO, ALESSANDRA; GIANNESSI, FLAVIA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2020Link identifier #identifier_person_145033-7 Dettaglio
• Introduction to the special issue: Extracellular vesicles and biological signal delivery in the inflammatory microenvironment, AFFABRIS, ELISABETTA; MANGINO, GIORGIO, , 2020Link identifier #identifier_person_184318-8 Dettaglio
• The role of extracellular vesicles as allies of HIV, HCV and SARS viruses, GIANNESSI, FLAVIA; AIELLO, ALESSANDRA; FRANCHI, FRANCESCA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2020Link identifier #identifier_person_142084-9 Dettaglio
• Purification and Characterization of Antibodies in Single-Chain Format against the E6 Oncoprotein of Human Papillomavirus Type 16, PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2018Link identifier #identifier_person_26158-10 Dettaglio
• The involvement of plasmacytoid cells in HIV infection and pathogenesis., AIELLO, ALESSANDRA; GIANNESSI, FLAVIA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2018Link identifier #identifier_person_32894-11 Dettaglio
• Staphylococcus aureus esx factors control human dendritic cell functions conditioning Th1/Th17 response, CRUCIANI, MELANIA; PERCARIO, ZULEMA ANTONIA; RIZZO, FABIANA; BRANDI, VALENTINA; POLTICELLI, FABIO; AFFABRIS, ELISABETTA, , 2017Link identifier #identifier_person_170185-12 Dettaglio
• A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models, PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2016Link identifier #identifier_person_136135-13 Dettaglio
• HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity, MANGINO, GIORGIO; FAMIGLIETTI, MARYLINDA; CAPONE, CATERINA; PERCARIO, ZULEMA ANTONIA; LEONE, STEFANO; PERSICHINI, TIZIANA; AFFABRIS, ELISABETTA, , 2015Link identifier #identifier_person_101772-14 Dettaglio
• Nef, the shuttling molecular adaptor of HIV, influences the cytokine network, PERCARIO, ZULEMA ANTONIA; ALI, MUHAMMAD; MANGINO, GIORGIO; AFFABRIS, ELISABETTA, , 2015Link identifier #identifier_person_154303-15 Dettaglio
• Role of the microenvironment in tumourigenesis: focus on virus-induced tumors, MANGINO, GIORGIO; AFFABRIS, ELISABETTA, , 2015Link identifier #identifier_person_126098-16 Dettaglio
• Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism., ARENACCIO, CLAUDIA; AFFABRIS, ELISABETTA, , 2014Link identifier #identifier_person_132111-17 Dettaglio
• In vivo antitumor effect of an intracellular single-chain antibody fragment against the E7 oncoprotein of human papillomavirus 16., PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2014Link identifier #identifier_person_166109-18 Dettaglio
• Effect of atrial natriuretic peptide on reactive oxygen species-induced by hydrogen peroxide in THP-1 monocytes: role in cell growth, migration and cytokine release., INCERPI, SANDRA; AFFABRIS, ELISABETTA, , 2013Link identifier #identifier_person_129429-19 Dettaglio
• Cancer Regulator MicroRNA: Potential Relevance in Diagnosis, Prognosis and Treatment of Cancer., MANGINO, GIORGIO; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2012Link identifier #identifier_person_84364-20 Dettaglio
• Exogenous Nef Induces Proinflammatory SignalingEvents in Murine Macrophages, MANGINO, GIORGIO; SERRA, VALERIA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2012Link identifier #identifier_person_125615-21 Dettaglio
• Interferon-β Induces Cellular Senescence in Cutaneous Human Papilloma Virus-Transformed Human Keratinocytes by Affecting p53 Transactivating Activity., PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2012Link identifier #identifier_person_149921-22 Dettaglio
• Nongenomic effects of thyroid hormones on the immune system cells: new targets, old players, AFFABRIS, ELISABETTA; INCERPI, SANDRA, , 2012Link identifier #identifier_person_91268-23 Dettaglio
• HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2, PERCARIO, ZULEMA ANTONIA; ACCONCIA, FILIPPO; CHIARABELLI, CRISTIANO; LEONE, STEFANO; NOTO, ALESSIA; POLTICELLI, FABIO; AFFABRIS, ELISABETTA, , 2011Link identifier #identifier_person_171341-24 Dettaglio
• HMGB1 and cord blood: its role as immuno-adjuvant factor in innate immunity, PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2011Link identifier #identifier_person_56030-25 Dettaglio
• The conserved acidic cluster domain of HIV-1 Nef is required to induces a proinflammatory state in primary macrophages: involvement of TNF alpha Receptor Associated Factor 2, CHIARABELLI, CRISTIANO, , 2011Link identifier #identifier_person_104079-26 Dettaglio
• Astrocytes contacting HIV-1-infected macrophages increase the release of CCL2 in response to the HIV-1-dependent enhancement of membrane-associated TNFalpha in macrophages, AFFABRIS, ELISABETTA, , 2010Link identifier #identifier_person_4756-27 Dettaglio
• Immunomodulatory activity of a plant extract containing human papillomavirus 16-E7 protein in human monocyte-derived dendritic cells, AFFABRIS, ELISABETTA, , 2009Link identifier #identifier_person_6215-28 Dettaglio
• Senescence and cell death pathways and their role in cancer therapeutic outcome, AFFABRIS, ELISABETTA, , 2009Link identifier #identifier_person_106762-29 Dettaglio
• In vitro treatment of human monocyte/macrophages with myristoylated recombinant Nef of HIV 1 leads to the activation of Mitogen-Activated Protein Kinases, IkB kinases and Interferon Regulatory Factor 3 and to the release of beta Interferon, AFFABRIS, ELISABETTA, , 2007Link identifier #identifier_person_121592-30 Dettaglio
• Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons, AFFABRIS, ELISABETTA, , 2007Link identifier #identifier_person_173366-31 Dettaglio
• TNF-related apoptosis-inducing ligand (TRAIL) as a pro-apoptotic signal transducer with cancer therapeutic potential., PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2005Link identifier #identifier_person_90538-32 Dettaglio
• TRAIL as a pro-apoptotic signal transducer with cancer therapeutic potential, AFFABRIS, ELISABETTA, , 2005Link identifier #identifier_person_53372-33 Dettaglio
• TRAIL is a key target in S-phase slowing-dependent apoptosis induced by Interferon-beta in cervical carcinoma cells, AFFABRIS, ELISABETTA, , 2005Link identifier #identifier_person_94883-34 Dettaglio
• HIV-1 Nef Activates STAT3 in Primary Human Monocyte/Macrophages through the Release of Soluble Factors: Involvement of Nef Domains Interacting with the Cell Endocytotic Machinery, AFFABRIS, ELISABETTA, , 2003Link identifier #identifier_person_194259-35 Dettaglio
• HIV-1 Nef Induces the Release of Inflammatory Factors from Human Monocyte/Macrophages: Involvement of Nef Endocytotic Signals and NF-kB Activation, AFFABRIS, ELISABETTA, , 2003Link identifier #identifier_person_173400-36 Dettaglio
• Review:IRF-1 as a negative regulator of cell proliferation, AFFABRIS, ELISABETTA, , 2002Link identifier #identifier_person_71679-37 Dettaglio
• HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors, AFFABRIS, ELISABETTA, , 2001Link identifier #identifier_person_292-38 Dettaglio
• Interferon beta induces S-phase slowing via up-regulated expression of PML in squamous carcinoma cells, AFFABRIS, ELISABETTA, , 2000Link identifier #identifier_person_126500-39 Dettaglio
• Retinoic acid is able to induce IRF-1 in squamous carcinoma cells via a STAT-1 independent signalling pathway, AFFABRIS, ELISABETTA, , 1999Link identifier #identifier_person_120483-40 Dettaglio
• Antiproliferative activity of interferon alfa and retinoic acid in SiHa carcinoma cells: the role of cell adhesion, AFFABRIS, ELISABETTA, , 1998Link identifier #identifier_person_73730-41 Dettaglio
• Apoptosis and growth inhibition of squamous carcinoma cells treated with IFN-alfa, IFN-beta and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21, AFFABRIS, ELISABETTA, , 1998Link identifier #identifier_person_156628-42 Dettaglio
• Retinoic acid and interferon inhibition of cell proliferation is associated with apoptosis in squamous carcinoma cell lines. Role of IRF-1 and TGAseII-dependent pathways, AFFABRIS, ELISABETTA, , 1997Link identifier #identifier_person_135478-43 Dettaglio
• Perspectives in interferon and cytokine research., AFFABRIS, ELISABETTA, , 1996Link identifier #identifier_person_168117-44 Dettaglio
• Hemin inhibits the interferon beta-induced antiviral state in established cell lines, AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_110666-45 Dettaglio
• IFN-alpha2b and retinoic acid combined treatment affects proliferation and gene expression of human cervical carcinoma cells, AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_3443-46 Dettaglio
• Inhibition of protein phosphorylation blocks interferon-induced gene expression and modulates expression of the JAK family protein tyrosine kinases, AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_169887-47 Dettaglio
• Staurosporine inhibits interferon alpha-induced gene expression in Friend erythroleukemia cells through a PKC independent pathway., AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_673-48 Dettaglio
• ACUTE REJECTION OF INTERFERON-TREATED LEUKEMIA-CELLS INJECTED INTO LETHALLY IRRADIATED SYNGENEIC MICE, AFFABRIS, ELISABETTA, , 1993Link identifier #identifier_person_148834-49 Dettaglio
• Friend virus-induced erythroleukemia: a model system to study erythroid differentiation and leukemia development, AFFABRIS, ELISABETTA, , 1993Link identifier #identifier_person_184508-50 Dettaglio
• Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin, AFFABRIS, ELISABETTA, , 1992Link identifier #identifier_person_140295-51 Dettaglio
• TRANSCRIPTIONAL INDUCTION OF H2 (CLASS-I) ANTIGENS AND BETA-2 MICROGLOBULIN BY INTERFERON-GAMMA IN INTERFERON-SENSITIVE AND INTERFERON-RESISTANT FRIEND-LEUKEMIA CELLS, AFFABRIS, ELISABETTA, , 1992Link identifier #identifier_person_119280-52 Dettaglio
• Intracellular heme coordinately modulates globin chains synthesis, transferrin receptor number and ferritin content in differentiating Friend erythroleukemia cells, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_118827-53 Dettaglio
• Positive modulation of hemoglobin, heme and transferrin receptor synthesis by murine interferons-alpha and -beta in differentiating Friend cells: pivotal role of heme synthesis, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_98602-54 Dettaglio
• Post-transcriptional regulation of interferon-beta expression in erythroid Friend cells treated with interferon-gamma, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_109773-55 Dettaglio
• Protein binding to the interferon response enhancer correlates with interferon-induction of 2-5A synthetase in normal and interferon-resistant Friend cells, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_172403-56 Dettaglio
• A full-lenght murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication, AFFABRIS, ELISABETTA, , 1990Link identifier #identifier_person_124604-57 Dettaglio
• Spectrum of biological activity of IFNs. In: "Lymphokines and interferons: from molecular biology to clinical trials", AFFABRIS, ELISABETTA, , 1990Link identifier #identifier_person_65942-58 Dettaglio
• Interferons and differentiation of Friend cells, AFFABRIS, ELISABETTA, , 1989Link identifier #identifier_person_97080-59 Dettaglio
• Poly (ADP-ribose) polymerase activity is inhibited by 2'-5'-oligoadenylates in mouse L-cells, AFFABRIS, ELISABETTA, , 1989Link identifier #identifier_person_64247-60 Dettaglio
• Interferons and oncogenes in the control of cell growth and differentiation: working hypothesis and experimental facts, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_164098-61 Dettaglio
• Interferons-alpha,beta and gamma-resistant Friend cell variants exhibiting receptor sites for Interferons but no induction of 2-5A synthetase and 67K protein kinase, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_71239-62 Dettaglio
• MONOCLONAL-ANTIBODIES ANTI-MURINE INTERFERON (IFN) BETA-NEUTRALIZE THE STIMULATION OF ERYTHROID-DIFFERENTIATION INDUCED BY TREATMENT OF FRIEND-CELLS WITH DIMETHYLSULFOXIDE AND MURINE FIBROBLAST IFN, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_90888-63 Dettaglio
• Opposite effects of murine interferons on erythroid differentiation of Friend cells, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_108926-64 Dettaglio
• Effect of mouse interferon alpha/beta on the expression of H-2 (class I) antigens and on the levels of 2'-5' oligoadenylate synthetase activity in interferon-sensitive and interferon-resistant Friend leukemia cell tumors in mice., AFFABRIS, ELISABETTA, , 1987Link identifier #identifier_person_1992-65 Dettaglio
• MOLECULAR MECHANISMS OF ACTION OF INTERFERONS IN THE FRIEND VIRUS-INDUCED LEUKEMIA-CELL SYSTEM, AFFABRIS, ELISABETTA, , 1987Link identifier #identifier_person_102303-66 Dettaglio
• 2',5'-oligoadenylate synthetase-uninducible alpha, beta interferon-resistant Friend cells develop an antiviral state when permeabilized with lysolecithin and treated with 2',5'- oligoadenylate oligomers, AFFABRIS, ELISABETTA, , 1986Link identifier #identifier_person_64103-67 Dettaglio
• Establishment of the antiviral state in alpha, beta interferon-resistant Friend cells treated with gamma interferon: induction of 67K protein kinase activity in absence of detectable 2-5A synthetase, AFFABRIS, ELISABETTA, , 1985Link identifier #identifier_person_147956-68 Dettaglio
• Subcellular distribution of 2'-5'-oligoadenylate synthetase in differentiating Friend leukemia cells, AFFABRIS, ELISABETTA, , 1985Link identifier #identifier_person_98229-69 Dettaglio
• The role of two interferon-induced enzymatic activities in erythroid differentiation of Friend cells., AFFABRIS, ELISABETTA, , 1985Link identifier #identifier_person_130033-70 Dettaglio
• Role of interferon and 2'-5'-olygoadenylate synthetase in erythroid differentiation of Friend leukemia cells, AFFABRIS, ELISABETTA, , 1984Link identifier #identifier_person_32189-71 Dettaglio
• 2-5A synthetase activity does not increase in interferon-resistent Friend leukemia cell variants treated with alpha/beta interferon despite the presence of high-affinity interferon receptor sites, AFFABRIS, ELISABETTA, , 1983Link identifier #identifier_person_175817-72 Dettaglio
• Isolation of interferon-resistant variants of Friend erythroleukemia cells: effects of interferon and ouabain, AFFABRIS, ELISABETTA, , 1982Link identifier #identifier_person_57731-73 Dettaglio
• Modulation of erythroid differentiation induced by DMSO in Friend cells treated with interferon: a clonal analysis, AFFABRIS, ELISABETTA, , 1982Link identifier #identifier_person_128851-74 Dettaglio
• Interactions of interferon with in vitro model systems involved in hematopoietic cell differentiation., AFFABRIS, ELISABETTA, , 1980Link identifier #identifier_person_123224-75 Dettaglio
• Erythroid differentiation of Friend erythroleukemia cells: a "variant" cell line endowed with an early expression of erythroid markers., AFFABRIS, ELISABETTA, , 1978Link identifier #identifier_person_81807-76 Dettaglio

Libro

• Link identifier #identifier_person_30668-77Dettaglio

Contributo in volume e atti di convegno

• PERCARIO, ZULEMA ANTONIA; MANGINO, GIORGIO; GALLO, VALENTINA; AFFABRIS, ELISABETTA, HIV-1 Nef Transfer and Intracellular Signalling in Uninfected Cells.(part 1, Chapter 3), vol. unico, pp. 61 78, 2011 Link identifier #identifier_person_142031-78Dettaglio
• AFFABRIS, ELISABETTA, Antiproliferative effect of interferon beta in mucosal and cutaneous Human Papilloma Virus (HPV) - transformed keratinocytes., CYTOKINE, issn 1043-4666, vol. 43, pp. 330 330, 2008 Link identifier #identifier_person_31162-79Dettaglio
• PERCARIO, ZULEMA ANTONIA; MANGINO, GIORGIO; LEONE, STEFANO; AFFABRIS, ELISABETTA, Recombinant myristoylated HIV-1 Nef protein is able to enter human primary macrophages and monocitic cell line THP-1 activating signal transduction events through a IRAK1 degradation – independent mechanism., 2008 Link identifier #identifier_person_158188-80Dettaglio
• MANGINO, GIORGIO; PERCARIO, ZULEMA ANTONIA; LEONE, STEFANO; LAURO, GIULIANA MARIA; AFFABRIS, ELISABETTA, Recombinant Nef protein induces inflammatory response and upregulation of inducible nitric oxide synthase expression in the murine microglial cell line BV-2., 2008 Link identifier #identifier_person_24149-81Dettaglio
• PERCARIO, ZULEMA ANTONIA; MANGINO, GIORGIO; AFFABRIS, ELISABETTA, The production of interferon-ß induced by HIV-1 Nef treatment of primary human monocyte-derived macrophages requires the PI3K/Akt pathway., 2008 Link identifier #identifier_person_97679-82Dettaglio
• AFFABRIS, ELISABETTA, Virus-cell interactions in Human Immunodeficiency Virus infection: recent advances in viral accessory proteins function., 2008 Link identifier #identifier_person_1257-83Dettaglio
• AFFABRIS, ELISABETTA, In vitro treatment of human monocyte-derived macrophages with HIV-1 protein Nef activates cellular signaling pathways leading to type I Interferon production, vol. Unico, pp. 105 111, 2006 Link identifier #identifier_person_35427-84Dettaglio