The course aims to provide students with an overview of naturally occurring compounds implicated in major biological processes, along with some aspects of their chemical behavior. Knowledge will be provided on the chemical synthesis of the main natural polymers through solid phase techniques and application of natural macromolecules in organic synthesis. Finally, we will know about the use of databases for the search for the chemical and biological properties of organic substances.
teacher profile teaching materials
ACETATE PATHWAY. AROMATIC POLYKETIDES, ANTHRAQUINONES, CANNABINOIDS, AFLATOXINS.
SHIKIMATE PATHWAY. SHIKIMIC ACID BIOSYNTHESIS. CINNAMIC ACIDS. LIGNINES. PHENYLPROPANOIDS. BENZOIC ACIDS. COUMARINS. FLAVONOIDS. TANNINS. ISOFLAVONES. TERPENOID QUINONES.
MEVALONATE PATHWAY. MEVALONIC ACID BIOGENESIS. BIOSYNTHESIS OF DIFFERENT CLASSES OF TERPENES. IRIDOIDS. GIBBERELLINS. HORMONES. ANIMAL AND HUMAN STEROIDS. PHYTOSTEROLS.
ALKALOIDS: DEFINITION AND NOMENCLATURE. BIOSYNTHESIS AND BIOLOGICAL ACTIVITY OF THE MAIN CLASSES OF NATURAL ALKALOIDS: COCAINE, NICOTINE, CURARE, MORPHINE, LOGANIN, LYSERGIC ACID, CONIINE.
CARBOHYDRATES: GENERALITIES. CYANOGENIC GLYCOSIDES. STREPTOMYCINS.
PEPTIDIC SECONDARY METABOLITES. INTERFERONS. OPIOID PEPTIDES. PEPTIDE TOXINS: RICIN AND BOTULIN. PENICILLINS.
PWP LESSON FILES GIVEN BY PROFESSOR
Fruizione: 20402508 CHIMICA DELLE SOSTANZE NATURALI E DELL'AMBIENTE in Biodiversità e gestione degli ecosistemi LM-6 N0 TOFANI DANIELA
Programme
INTRODUCTION TO NATURAL PRODUCTS CHEMISTRY. MAIN FEATURES OF SECONDARY METABOLISM.ACETATE PATHWAY. AROMATIC POLYKETIDES, ANTHRAQUINONES, CANNABINOIDS, AFLATOXINS.
SHIKIMATE PATHWAY. SHIKIMIC ACID BIOSYNTHESIS. CINNAMIC ACIDS. LIGNINES. PHENYLPROPANOIDS. BENZOIC ACIDS. COUMARINS. FLAVONOIDS. TANNINS. ISOFLAVONES. TERPENOID QUINONES.
MEVALONATE PATHWAY. MEVALONIC ACID BIOGENESIS. BIOSYNTHESIS OF DIFFERENT CLASSES OF TERPENES. IRIDOIDS. GIBBERELLINS. HORMONES. ANIMAL AND HUMAN STEROIDS. PHYTOSTEROLS.
ALKALOIDS: DEFINITION AND NOMENCLATURE. BIOSYNTHESIS AND BIOLOGICAL ACTIVITY OF THE MAIN CLASSES OF NATURAL ALKALOIDS: COCAINE, NICOTINE, CURARE, MORPHINE, LOGANIN, LYSERGIC ACID, CONIINE.
CARBOHYDRATES: GENERALITIES. CYANOGENIC GLYCOSIDES. STREPTOMYCINS.
PEPTIDIC SECONDARY METABOLITES. INTERFERONS. OPIOID PEPTIDES. PEPTIDE TOXINS: RICIN AND BOTULIN. PENICILLINS.
Core Documentation
P.M. DEWICK : CHIMICA, BIOSINTESI E BIOATTIVITA' DELLE SOSTANZE NATURALI. EDIZIONI PICCINPWP LESSON FILES GIVEN BY PROFESSOR
Type of delivery of the course
Lectures are held using slides that will be made available to the students. Some monographs will also be presented on particular molecules of high biological and/or pharmacological interest.Type of evaluation
The student must present an oral essay, to be presented with the help of slides previously prepared, on a biologically active compound by analyzing its biosynthesis, biological activity and, possibly, the pharmacological, nutraceutical or food applications.