The module aims to provide the basics of: purine and pyrimidine nucleotides. Structure of biological macromolecules informational. Structure of prokaryotic and eukaryotic chromosomes. Replication, transcription and translation. Recombinant DNA and genetically modified organisms.
Proteins: Structure of proteins and examples of structure-function relationships.
Enzymes and enzymatic catalysis: active site concept and specificity; the Michaelis-Menten equation.
Metabolism of carbohydrates, lipids, proteins and nucleic acids: glycolysis and alcoholic fermentation and synthesis of lactate; citric acid cycle and pentose phosphate pathway; fatty acid metabolism; transformation of amino acids; urea cycle.
Bioenergetics and oxidative phosphorylation: the respiratory chain and oxidative phosphorylation.
Proteins: Structure of proteins and examples of structure-function relationships.
Enzymes and enzymatic catalysis: active site concept and specificity; the Michaelis-Menten equation.
Metabolism of carbohydrates, lipids, proteins and nucleic acids: glycolysis and alcoholic fermentation and synthesis of lactate; citric acid cycle and pentose phosphate pathway; fatty acid metabolism; transformation of amino acids; urea cycle.
Bioenergetics and oxidative phosphorylation: the respiratory chain and oxidative phosphorylation.
teacher profile teaching materials
Carbohydrates, Lipids, Amino acids,
proteins: structure of proteins and examples of structure-function relationships.
enzymes and enzymatic catalysis: Definition of active site and substrate specificity; the Michaelis-Menten equation, enzyme inhibition.
Introduction to aerobic and anaerobic metabolism
Metabolism of carbohydrates, lipids and nitrogen compounds
Energy production in mitochondria
Elementi di biologia e genetica. Sadana D., Hillis DM., Heller Hc, Berenbaum Mr. Ed. Zanichelli, 2014.
Lecture notes and calculation exercises will be provided
The professor receives every day from 8.00 to 9.00 or by appointment via e-mail: giovanni.antonini@uniroma3.it
Programme
The Course aims to provide students with basic knowledge relating to biochemistry and cellular metabolism.Carbohydrates, Lipids, Amino acids,
proteins: structure of proteins and examples of structure-function relationships.
enzymes and enzymatic catalysis: Definition of active site and substrate specificity; the Michaelis-Menten equation, enzyme inhibition.
Introduction to aerobic and anaerobic metabolism
Metabolism of carbohydrates, lipids and nitrogen compounds
Energy production in mitochondria
Core Documentation
Chimica, biochimica e biologia applicata. Stefani M., Taddei N. ed. Zanichelli, 2015.Elementi di biologia e genetica. Sadana D., Hillis DM., Heller Hc, Berenbaum Mr. Ed. Zanichelli, 2014.
Lecture notes and calculation exercises will be provided
The professor receives every day from 8.00 to 9.00 or by appointment via e-mail: giovanni.antonini@uniroma3.it
Type of delivery of the course
The course will take place with lecturesType of evaluation
The written test will focus on a brief description of 2-4 topics held studied the course. The score will take into account both the knowledge of the subject and the ability to present it synthetically. Mid-term tests will be carried out with the attribution of a score effective for the final vote teacher profile teaching materials
Laboratory activities.
1. Chimica, biochimica e biologia applicata. Stefani M., Taddei N. ed. Zanichelli, 2015.
2. Elementi di biologia e genetica. Sadana D., Hillis DM., Heller Hc, Berenbaum Mr. Ed. Zanichelli, 2014.
Lecture slides will be provided.
The professor receives every day from 10.00 to 11.00 by appointment via e-mail: manuela.cervelli@uniroma3.it
Programme
PURINE AND PYRIMIDINE NUCLEOTIDES: STRUCTURE OF BIOLOGICAL MACROMOLECULES; STRUCTURE OF PROKARYOTIC AND EUKARYOTIC CHROMOSOMES; REPLICATION, TRANSCRIPTION AND TRANSLATION; RECOMBINANT DNA AND GENETICALLY MODIFIED ORGANISMS.Laboratory activities.
Core Documentation
Recommended textbooks:1. Chimica, biochimica e biologia applicata. Stefani M., Taddei N. ed. Zanichelli, 2015.
2. Elementi di biologia e genetica. Sadana D., Hillis DM., Heller Hc, Berenbaum Mr. Ed. Zanichelli, 2014.
Lecture slides will be provided.
The professor receives every day from 10.00 to 11.00 by appointment via e-mail: manuela.cervelli@uniroma3.it
Type of delivery of the course
The course will take place with lectures and training in didactic laboratories.Type of evaluation
The written test will focus on a brief description of 2-4 topics held studied the course. The score will take into account both the knowledge of the subject and the ability to present it synthetically. Mid-term tests will be carried out with the attribution of a score effective for the final vote.