20410228 - FISIOLOGIA GENERALE

The main goals of this course are:
i) supply a strong and up-to-date knowledge on the bases of animal cell functions,
ii) develop the student’s knowledge on the dynamic integration of general functions into organs, systems and apparatuses,
iii) introduce the mechanisms of control of functions in healthy organisms,
iv) supply the students with the tools necessary to approach the study of complexity and emergent proprieties of functions,
v) develop student’s critical approach to experimental data and ability to problem solving.
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Programme

MEMBRANE DYNAMIC (0.5 CFU): STRUCTURE, FUNCTIONS AND DYNAMICS OF CELL PLASMA MEMBRANES. JUNCTIONS, CHANNELS, RECEPTORS. PERMEABILITY, DIFFUSION, OSMOSYS, TONICITY. PLASMA MEMBRANE TRANSPORT SYSTEMS: FACILITATE, PRIMARY AND SECONDARY ACTIVE TRANSPORT. ENDOCYTOSIS-EXOCYTOSIS. ABSORPTION.

HOMEOSTASIS AND CONTROL (2 CFU):ORGANIZATION OF CENTRAL AND AUTONOMOUS NERVOUS SYSTEM. ELECTRICAL PROPERTIES OF THE PLASMA MEMBRANES, GENESIS OF THE TRANSPLASMA MEMBRANE POTENTIAL, EXCITABILITY, RESTING MEMBRANE POTENTIAL, ELECTROTONIC AND ACTION POTENTIAL. PROPAGATION AND TRANSMISSION OF ELECTRIC SIGNALS. SYNAPSES. SOMATIC AND AUTONOMOUS REFLEX ARC. BASIC SENSORY PHYSIOLOGY AND RECEPTORS. HORMONES. CELL COMMUNICATION, GENERAL PROPERTIES OF THE ENDOCRINE SYSTEM, CHEMICAL STRUCTURE AND RELEASE OF HORMONES. HORMONE SIGNAL TRANSDUCTION.

FUNCTION OF ORGANS AND SYSTEMS (4 CFU): MUSCLE SYSTEM. SKELETAL, SMOOTH, CARDIAC MUSCLE. MECHANIC OF THE SKELETAL MUSCLE CONTRACTION. MYOGRAM. REFRACTORY PERIOD. TETANIC CONTRACTION. CONTROL OF THE MUSCLE CONTRACTION. CARDIOVASCULAR SYSTEM. ELECTRICAL PROPERTIES OF THE HEART, POTENTIALS OF PACEMAKER CELLS AND WORKING MYOCARDIUM, THE HEART AS A PUMP. INTRINSIC AND EXTRINSIC REGULATION OF THE HEART CARDIAC OUTPUT. VASCULAR SYSTEM, FLUX, ARTERY PRESSURE AND ITS REGULATION. THE BLOOD. PROPERTIES, GLOBULAR RESISTANCE, BLOOD DISTRIBUTION TO TISSUES. COAGULATION. RESPIRATORY SYSTEM. RESPIRATORY MECHANIC, VENTILATION, EXCHANGE AND TRANSPORT OF GASES, PH REGULATION, REGULATION OF VENTILATION. RENAL SYSTEM. GLOMERULAR FILTRATION, REASSORBTION, SECRETION, EXCRETION. HORMONE REGULATION OF THE RENAL FUNCTION. DIGESTIVE SYSTEM. MOTILITY, SECRETION, DIGESTION, ABSORPTION OF CARBOHYDRATES, LIPIDS AND PROTEINS.

INTEGRATED PHYSIOLOGY (1.5 CFU): BASIS OF NUTRITION PHYSIOLOGY, METABOLISM AND ENERGETIC BALANCE. HOMEOSTATIC CONTROL OF ENERGETIC METABOLISM BY INSULIN AND GLUCAGON, THERMOREGULATION. HYDRO-ELECTROLYTIC HOMEOSTASIS. ACID-BASE EQUILIBRIUM. BODY ACCLIMATATION TO EXERCISE AND ENVIRONMENTAL CHANGES


Core Documentation

Taglietti V Fondamenti di Fisiologia Generale e Integrata 2019 EDISES
Cindy L. Stanfield Fisiologia 2012 EDISES
D.U. Silverthorn FISIOLOGIA UMANA 2020 PEARSON, MILANO –TORINO, ITALIA.


Type of delivery of the course

Three different written examinations are performed during the course. Hovewer the student is free to accept the classification or to ask for oral examination

Type of evaluation

The course of Physiology constists of lectures and pratical training in laboratory PRACTICAL TRAINING IN CHEMICAL LABORATORY (1 CFU): OSMOTIC PRESSURE, BLOOD (GLOBULAR RESISTANCE), CARDIOVASCULAR, RESPIRATION (it is posponed during pandemic).

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Programme

Laboratory practice exercise:
Practice 1: Osmosis
Practice 2: Globular Resistance
Practice 3: Arterial Pressure
Practice 4: Spirometry

Core Documentation

D.U. Silverthorn Human Physiology 2020 PEARSON, MILANO –TORINO, ITALIA.

Reference Bibliography

None at this point

Type of delivery of the course

Laboratory practice exercise

Attendance

None at this point

Type of evaluation

Self-evaluation

teacher profile | teaching materials

Programme

Practical Labs

Core Documentation

None at this point.

Reference Bibliography

None at this point.

Type of delivery of the course

Lab work

Type of evaluation

Oral Exam

teacher profile | teaching materials

Programme


Laboratory activities (eritrocyte resistance, osmosis, blood pressure measurement)

Core Documentation

Experimental protocols provided to the student

Type of delivery of the course

laboratory practice

Type of evaluation

Oral exam