Programme

Gene and chromosomal mutations, DNA repair systems, effects of genome alterations in somatic and germ cells. Physical mutagens, chemical mutagens and their metabolism. Genotoxic pollutants in air, water and soil matrices. "In vitro" tests in prokaryotic and eukaryotic cells, "in vivo" tests on model organisms. Application of mutaganesis tests to environmental and human populations biomonitoring. Elements of environmental legislation.

Core Documentation

genomics and enviromental mutagenesis L. Migliore, ed Zanichelli
OFFICE HOURS AT THE END OF THE CLASS AND BY PRIOR APPOINTMENT

Type of delivery of the course

frontal classes

Type of evaluation

the oral test will be based on a discussion of several topics related to the program.