To provide knowledge on mutagenesis and repair of genetic damage starting from the concepts of classical and molecular cytogenetics. To provide theoretical and practical skills for the execution of genotoxicity tests and for the criteria for the identification of bioindicator organisms suitable for environmental biomonitoring, aimed at assessing the genotoxic risk in different environmental matrices.
teacher profile teaching materials
OFFICE HOURS AT THE END OF THE CLASS AND BY PRIOR APPOINTMENT
Programme
Gene and chromosomal mutations, DNA repair systems, effects of genome alterations in somatic and germ cells. Physical mutagens, chemical mutagens and their metabolism. Genotoxic pollutants in air, water and soil matrices. "In vitro" tests in prokaryotic and eukaryotic cells, "in vivo" tests on model organisms. Application of mutaganesis tests to environmental and human populations biomonitoring. Elements of environmental legislation.Core Documentation
genomics and enviromental mutagenesis L. Migliore, ed ZanichelliOFFICE HOURS AT THE END OF THE CLASS AND BY PRIOR APPOINTMENT
Type of delivery of the course
frontal classesType of evaluation
the oral test will be based on a discussion of several topics related to the program.