20410228 - FISIOLOGIA GENERALE

The main goals of this course are:
i) supply a strong and up-to-date knowledge on the bases of animal cell functions,
ii) develop the student’s knowledge on the dynamic integration of general functions into organs, systems and apparatuses,
iii) introduce the mechanisms of control of functions in healthy organisms,
iv) supply the students with the tools necessary to approach the study of complexity and emergent proprieties of functions,
v) develop student’s critical approach to experimental data and ability to problem solving.
teacher profile | teaching materials

Programme

Laboratory practice exercise:
Practice 1: Osmosis
Practice 2: Globular Resistance
Practice 3: Arterial Pressure
Practice 4: Spirometry

Prerequisiti

Biochemistry, Comparative anatomy, Physics

Core Documentation

D.U. Silverthorn Human Physiology 2020 PEARSON, MILANO –TORINO, ITALIA.

Reference Bibliography

None at this point

Type of delivery of the course

Laboratory practice exercise

Attendance

None at this point

Type of evaluation

Self-evaluation

teacher profile | teaching materials

Programme

Unit I: MEMBRANE DYNAMICS: STRUCTURE, FUNCTIONS, AND DYNAMICS OF CELL MEMBRANES. PERMEABILITY, DIFFUSION, OSMOSIS, TONICITY. MEMBRANE TRANSPORT: FACILITATED, PRIMARY ACTIVE, AND SECONDARY ACTIVE. ENDOCYTOSIS-EXOCYTOSIS. ABSORPTION.

Unit II: HOMEOSTASIS AND CONTROL: ORGANIZATION OF THE CENTRAL AND AUTONOMOUS NERVOUS SYSTEMS. ELECTRICAL PROPERTIES OF THE CELL MEMBRANE, GENESIS OF THE TRANSMEMBRANE POTENTIAL, EXCITABILITY, RESTING POTENTIAL, ELECTROTONE, ACTION POTENTIAL. PROPAGATION AND TRANSMISSION OF ELECTRICAL SIGNALS. SYNAPSES. SOMATIC AND AUTONOMIC REFLEX ARCH. ELEMENTS OF SENSORY PHYSIOLOGY AND SENSORY RECEPTORS. HORMONES. CELLULAR COMMUNICATION, GENERAL INFORMATION ON THE ENDOCRINE SYSTEM, CHEMICAL NATURE AND RELEASE OF HORMONES. HORMONE SIGNAL TRANSDUCTION.

Unit III: FUNCTION OF ORGANS AND SYSTEMS: MUSCULAR SYSTEM. SKELETAL, SMOOTH, AND CARDIAC MUSCLES. MECHANICS OF MUSCLE CONTRACTION. MYOGRAMS. REFRACTORY PERIOD. TETANUS. CONTROL OF MUSCLE MOVEMENT. CARDIOVASCULAR SYSTEM. ELECTRICAL PROPERTIES OF THE HEART, POTENTIALS OF PACEMAKER CELLS AND WORKING MYOCARDIUM, THE HEART AS A PUMP. INTRINSIC AND EXTRINSIC REGULATION OF CARDIAC OUTPUT. BLOOD VESSELS, FLOW, ARTERIAL PRESSURE AND ITS REGULATION. BLOOD. PROPERTIES OF BLOOD, GLOBULAR RESISTANCE, DISTRIBUTION OF BLOOD TO TISSUES, COAGULATION. RESPIRATORY SYSTEM. RESPIRATORY MECHANICS, VENTILATION, GAS EXCHANGE AND TRANSPORT, PH REGULATION, VENTILATION REGULATION. RENAL SYSTEM. GLOMERULAR FILTRATION, REABSORPTION, SECRETION, EXCRETION. HORMONAL REGULATION OF RENAL FUNCTION. DIGESTIVE SYSTEM. MOTILITY, SECRETION, DIGESTION, ABSORPTION OF CARBOHYDRATES, LIPIDS, AND PROTEINS.

Unit IV: INTEGRATED PHYSIOLOGY: ELEMENTS OF NUTRITION PHYSIOLOGY, METABOLISM, AND ENERGY BALANCE. HOMEOSTATIC CONTROL OF ENERGY METABOLISM BY INSULIN AND GLUCAGON. HYDRO-ELECTROLYTIC BALANCE. WATER-SALT BALANCE.

PRACTICAL LABORATORY EXERCISES ARE PLANNED (1CFU)


Prerequisiti

The course requires basic knowledge of Comparative Anatomy and Developmental Biology, Cytology and Histology, Physics, Biochemistry, and Organic Chemistry, acquired during the preceding years of the degree programme. Students must have passed these examinations to meet the formal prerequisites and possess the necessary foundational knowledge.

Core Documentation

Fisiologia Medica Vol 1 e 2 a cura di Fiorenzo Conti
Taglietti V Fondamenti di Fisiologia Generale e Integrata 2019 EDISES
Cindy L. Stanfield Fisiologia 2012 EDISES
D.U. Silverthorn FISIOLOGIA UMANA 2020 PEARSON, MILANO –TORINO, ITALIA.


Reference Bibliography

Fisiologia Medica Vol 1 e 2 a cura di Fiorenzo Conti Taglietti V Fondamenti di Fisiologia Generale e Integrata 2019 EDISES Cindy L. Stanfield Fisiologia 2012 EDISES D.U. Silverthorn FISIOLOGIA UMANA 2020 PEARSON, MILANO –TORINO, ITALIA.

Attendance

La frequenza non è obbligatoria ma fortemente consigliata.

Type of evaluation

Assessment will consist of an oral examination, generally lasting approximately 30 minutes, during which students will be asked three questions. Each question will cover one part of the course. Students will be examined by two members of the examination board. The first examiner will ask two questions, and the second examiner will ask one question. The final grade will reflect the assessments of both examiners. The examiners will assess the depth and quality of students’ knowledge of the topics, their use of appropriate terminology, and their ability to make connections between different parts of the course. The final grade will reflect the assessments of both examiners and will be expressed on a scale of 30. If the two examiners’ assessments differ substantially, the final grade will be calculated as the average of the marks awarded for the three questions.

teacher profile | teaching materials

Programme

Lab practice about:
Osmosis, eritrocyte resistence, spirometric and blood pressure measurements.

Prerequisiti

See General Physiology course Prof.Filippo Acconcia

Core Documentation

Books indicated by prof. Filippo Acconcia chief of the course.

Type of delivery of the course

laboratory practice

Attendance

To attend lab practice is strongly suggested

Type of evaluation

See general physiology course, prof. Filippo Acconcia