The course aims to provide students with fundamental knowledge on the basic principles of toxicology. In particular, the toxicodynamic and toxicokinetic mechanisms that are behind the toxic effects produced by different natural and synthesized xenobiotics, and the process of evaluation of toxicological risks will be analyzed. This knowledge will allow students to acquire specific professional skills useful in experimental and analytical research laboratories and to carry out professional activities in the pharmaco-toxicological field to protect the safety of the environment, food, cosmetic products and drugs, of both synthetic and natural origin.