20410525 - Laboratorio di chimica fisica

The course covers the key concepts of the principal topics in Chemical Physics: thermodynamics, kinetics and quantum mechanics. Students will be introduced to the experimental aspects of Chemical Physics, and they will familiarize with the theoretical and experimental aspects of spectroscopic methods commonly used in the investigation of biomaterials and biomolecules. The course aims to develop the skills necessary to autonomously apply basic physico-chemical concepts and spectroscopic techniques (UV-vis absorption and emission, FT-IR, XPS) to the study of biomolecules.
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Mutuazione: 20410525 Laboratorio di chimica fisica in Biologia per la ricerca molecolare, cellulare e fisiopatologica LM-6 BATTOCCHIO CHIARA

Programme

ATOMIC STRUCTURE: ATOMIC MODELS, ATOMIC ORBITALS. CHEMICAL BOND: MOLECULAR ORBITALS. LAWS OF THERMODYNAMICS: ENERGY, WORK AND HEAT. STATE FUNCTIONS (RECALL): INTERNAL ENERGY, ENTHALPY, ENTROPY, FREE ENERGY. INTRODUCTION TO THE RADIATION-MATTER INTERACTION (CLASSICAL MODEL). SPECTROSCOPIES: VIBRATIONAL SPECTROSCOPY (FT-IR), ELECTRONIC SPECTROSCOPIES. UV-VIS ABSORPTION AND EMISSION. X-RAYS PHOTOEMISSION SPECTROSCOPY (XPS). INSTRUMENTATION. EXAMPLES OF APPLICATIONS OF FT-IR, UV-VIS and XPS SPECTROSCOPIES TO THE INVESTIGATION OF THE ELECTRONIC AND CHEMICAL STRUCTURE OF BIOMOLECULES.

Core Documentation

PETER ATKINS, JULIO DE PAULA: Physical Chemistry for the Life Sciences. ISBN: 9780199564286; slides can be downloaded from the Moodle page.


Type of delivery of the course

Theoretical lessons and experiments carried out in small groups (3-4 students) with the instrumentation in the CEDIC Laboratory and Materials Chemistry Laboratory. Absorption and Emission UV-visible spectroscopy, FT-IR and IRRAS, XPS.

Type of evaluation

students are required to write scientific reports about the experiments carried out in the physical chemistry laboratory; such reports are evaluated and discussed during the oral exam.