The aim of the course is to introduce students to the “inorganic biofactors”, starting from their biochemical role to the analysis of their impact on human health.
Moreover, the course will provide student the essential knowledge for understanding of the biochemical and molecular mechanism underlying metabolic, mitochondrial and neoplastic diseases.
Moreover, the course will provide student the essential knowledge for understanding of the biochemical and molecular mechanism underlying metabolic, mitochondrial and neoplastic diseases.
teacher profile teaching materials
Support texts:
Siliprandi & Tettamanti "Biochimica Medica - strutturale, metabolica e funzionale" Ed. Piccin
- Chiurchiù & Maccarrone "I radicali liberi e la loro rilevanza in biomedicina: dai meccanismi molecolari alle prospettive terapeutiche" Ed Piccin
RECEPTION TIME: Mondays 10 am (please fix an appointment, alessandra.dimasi@uniroma3.it)
Mutuazione: 20402360 BIOCHIMICA CELLULARE in Biologia Molecolare, Cellulare e della Salute LM-6 DI MASI ALESSANDRA
Programme
HEME-PROTEINS. HEME METABOLISM AND RELATED DISEASES. HEME BIOSYNTHESIS AND RELATED DISEASES. IRON METABOLISM AND RELATED DISEASES. INORGANIC BIOFACTORS: OXYGEN, CARBON MONOXIDE, NITROGEN MONOXIDE, HYDROGEN SULFIDE. BIOCHEMICAL AND CELLULAR ROLES OF THE INORGANIC BIOFACTORS. ROLE IOF THE INORGANIC BIOFACTORS IN HUMANN DISEASES ONSET. THE THERAPEUTIC USE OF THE INORGANIC BIOFACTORS. REACTIVE OXYGEN AND NITROGEN SPECIES. MITOCHONDRIAL DISEASES. THE ENERGETIC MATTER OF CANCER CELLS. THE METABOLIC REQUIREMENTS OF CANCER CELLS: THE WARBURG AND REVERSE WARBURG EFFECTS.Core Documentation
SCIENTIFIC PAPERS SUPPLIED BY THE TEACHER.Support texts:
Siliprandi & Tettamanti "Biochimica Medica - strutturale, metabolica e funzionale" Ed. Piccin
- Chiurchiù & Maccarrone "I radicali liberi e la loro rilevanza in biomedicina: dai meccanismi molecolari alle prospettive terapeutiche" Ed Piccin
RECEPTION TIME: Mondays 10 am (please fix an appointment, alessandra.dimasi@uniroma3.it)
Type of delivery of the course
The course of Cellular Biochemistry is a theoretical course that takes place in the second semester (March-May) of the first year and is divided into 4 hours of lectures per week with the use of PowerPoint presentations. Lessons will be provided both in person and on a telematic platform depending on the pandemic situation.Attendance
OptionalType of evaluation
The exam consists of two midterm tests in the form of 3 open questions. The first test will take place around mid-November, the second at the end of the course. The final grade will be derived from the average of the grades obtained in the two midterm tests. In the event that the student has not taken one of the two midterm tests or wishes to raise the grade obtained in one of them, he/she may take the oral examination with respect to the parts of the program covered by the tests on the established appeal dates. A student who does not intend to take the midterm tests during the semester may take the oral examination directly on the established appeal dates. The final grade will evaluate the following parameters: a) Appropriateness, correctness, and congruity of acquired knowledge and skills; b) appropriate use of the specific language of the discipline; c) Expressive capacity; d) Logical skills; e) Synthesis skills; f) Ability to link different topics. Consequently, the judgment could be: a) Sufficient (from 18 to 20/30) b) Fair (from 21 to 23) c) Voucher (from 24 to 26) d) Excellent (from 27 to 29) e) Excellent (30) Praise is attributed to candidates clearly above the average, and whose possible notional, expressive, conceptual and logical limits are altogether irrelevant.