The course of Antimicrobial immunity and immunodiagnostic” aims to provide students with competences concerning the different modes of host-pathogen interaction, with particular reference to the mechanisms of the anti-infective immune response, the possibility of manipulating it, and how the immune response to microbes may be used in the diagnostic.
Students who have passed the exam will know and understand (acquired knowledge) (i) basic principles of the immune system functions, (ii) principles of cellular and molecular mechanisms of the antimicrobial immunity, (iii) vaccinology principles, (iv) immunological methodologies used in the diagnosis of infectious diseases.
Students who have passed the exam will be able to (acquired skills) (i) understand and analyse basic test regarding the field (ii) critically analyse issues related to the immune response to microbes (iii) identify and develop key themes to build educational paths in the specific field.
Students who have passed the exam will know and understand (acquired knowledge) (i) basic principles of the immune system functions, (ii) principles of cellular and molecular mechanisms of the antimicrobial immunity, (iii) vaccinology principles, (iv) immunological methodologies used in the diagnosis of infectious diseases.
Students who have passed the exam will be able to (acquired skills) (i) understand and analyse basic test regarding the field (ii) critically analyse issues related to the immune response to microbes (iii) identify and develop key themes to build educational paths in the specific field.
teacher profile teaching materials
The fisico-chemical barriers and the lymphatic system
The complement system and its role in the antimicrobial response
Innate immunity and recognition of PAMPs (Pathogen Associated Moecular Patterns)
The cytokines
The structure of the antibodies, T cell receptor (TCR) and B cell receptor (BCR), and the major histocompatibility complex
Signal transduction of the TCR and BCR
T cell activation
Humoral response to microbes
Evasion of the immune response by microrganisms
Coordination of innate and adaptive immune response to microbes
Mucosal immunity and the role of microbiota
Vaccines and infection
Immunodeficiency and HIV infection
Autophagy and immune response
Diagnosis of viral and bacterial infection based on the immune response
Flowcytometry and the analysis of the immune system
the professor makes the slides available to the students.
Mutuazione: 20410767 Immunità antimicrobica e immunodiagnostica in Biologia Molecolare, Cellulare e della Salute LM-6 SACCHI ALESSANDRA
Programme
Introduction; Antigene definition; the cells of the immune systemThe fisico-chemical barriers and the lymphatic system
The complement system and its role in the antimicrobial response
Innate immunity and recognition of PAMPs (Pathogen Associated Moecular Patterns)
The cytokines
The structure of the antibodies, T cell receptor (TCR) and B cell receptor (BCR), and the major histocompatibility complex
Signal transduction of the TCR and BCR
T cell activation
Humoral response to microbes
Evasion of the immune response by microrganisms
Coordination of innate and adaptive immune response to microbes
Mucosal immunity and the role of microbiota
Vaccines and infection
Immunodeficiency and HIV infection
Autophagy and immune response
Diagnosis of viral and bacterial infection based on the immune response
Flowcytometry and the analysis of the immune system
Core Documentation
Janaway's Immunobiology (Piccin); Immunologia cellulare e molecolare (Feltrinelli)the professor makes the slides available to the students.
Attendance
Students are strongly advised to follow the lessons of the course to optimize learning.Type of evaluation
Oral exam with questions related to the topics covered by the program of the course. The questions are aimed at ascertaining the student's knowledge, reasoning skills