20410809 - ANALYTICAL CHEMISTRY

Learning Objectives Introduction to the practice of chemical analysis. This course adresses the practical aspect of analytical techniques with the aim of making the student able to move, organize and carry out chemical analyses. Knowledge and application of basic principles of analytical chemistry for determining bioactive compounds.
teacher profile | teaching materials

Programme

Introduction to analytical chemistry
Glassware and laboratory equipment
Measurement errors
- Classic methods of analysis: Gravimetric analyses; Volumetric analyses: acid-base, redox, complexation and precipitation titrations
- Analysis with electrochemical methods: direct potentiometry and potentiometric titrations
- Analysis with spectrochemical methods: molecular absorption spectroscopy (UV-VIs and IR); fluorescence spectroscopy; atomic emission and absorption spectroscopy; mass spectrometry
- Analysis methods by phase distribution: GC and HPLC chromatography
- Introduction to innovative pharmaceutical formulations (i.e., biologics and nanoformulations)
- Analytical methods and techniques to analyze innovative pharmaceutical formulations
- Training on dynamic light scattering






Core Documentation

D.S. Hage, J.D. Carr "Analytical Chemistry and Quantitative analysis"
F.J.Holler, S.R. Crouch "Fundamentals of Analytical Chemistry" Feltrinelli


Attendance

Attendance is strongly recommended for lessons, mandatory for laboratory experiences

Type of evaluation

The evaluation will focus on the result of the oral exam; the exam will last approximately 30 minutes and two questions will be asked, one on classical analytical chemistry and one on instrumental analysis methods and advanced methodologies. In the evaluation of the exam, the determination of the final grade will take into account the level and quality of knowledge of the topics as well as the use of appropriate vocabulary for analytical chemistry. The quality of the written reports presented will also be taken into consideration.

teacher profile | teaching materials

Programme

Introduction to analytical chemistry
Glassware and laboratory equipment
Measurement errors
- Classic methods of analysis: Gravimetric analyses; Volumetric analyses: acid-base, redox, complexation and precipitation titrations
- Analysis with electrochemical methods: direct potentiometry and potentiometric titrations
- Analysis with spectrochemical methods: molecular absorption spectroscopy (UV-VIs and IR); fluorescence spectroscopy; atomic emission and absorption spectroscopy; mass spectrometry
- Analysis methods by phase distribution: GC and HPLC chromatography
- Introduction to innovative pharmaceutical formulations (i.e., biologics and nanoformulations)
- Analytical methods and techniques to analyze innovative pharmaceutical formulations
- Training on dynamic light scattering


Core Documentation

Ijeoma F. Uchegbu, Andreas G. Schatzlein, Woei Ping Cheng, Aikaterini Lalatsa
Fundamentals of Pharmaceutical Nanoscience, Springer

Vladimir P. Torchlin
Nanoparticulates as Drug Carriers, Imperial College Press

Harry F. Tibbals
Medical Nanotechnology and Nanomedicine, CRC Press

Abdel Salam Hamdy, Makhlouf Nedal, Yusuf Abu-Thabit
Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume I e II, Woodhead Publishing

Attendance

Attendance not mandatory